{"id":251,"date":"2023-07-31T01:06:33","date_gmt":"2023-07-31T01:06:33","guid":{"rendered":"https:\/\/tracingrace.iastatedigital.org\/asian-womeninstem-isu\/?p=251"},"modified":"2023-09-11T03:27:59","modified_gmt":"2023-09-11T03:27:59","slug":"faculty-profiles-4","status":"publish","type":"post","link":"https:\/\/tracingrace.iastatedigital.org\/asian-womeninstem-isu\/uncategorized\/faculty-profiles-4\/","title":{"rendered":"Faculty Profiles"},"content":{"rendered":"\n<div class=\"wp-block-cover alignfull\" style=\"min-height:124px;aspect-ratio:unset;\"><span aria-hidden=\"true\" class=\"wp-block-cover__background has-background-dim\"><\/span><img loading=\"lazy\" decoding=\"async\" width=\"1920\" height=\"1079\" class=\"wp-block-cover__image-background wp-image-66\" alt=\"\" src=\"https:\/\/tracingrace.iastatedigital.org\/asian-womeninstem-isu\/wp-content\/uploads\/2023\/07\/cropped-IowaStateUniversity-3.jpeg\" data-object-fit=\"cover\" srcset=\"https:\/\/tracingrace.iastatedigital.org\/asian-womeninstem-isu\/wp-content\/uploads\/2023\/07\/cropped-IowaStateUniversity-3.jpeg 1920w, https:\/\/tracingrace.iastatedigital.org\/asian-womeninstem-isu\/wp-content\/uploads\/2023\/07\/cropped-IowaStateUniversity-3-300x169.jpeg 300w, https:\/\/tracingrace.iastatedigital.org\/asian-womeninstem-isu\/wp-content\/uploads\/2023\/07\/cropped-IowaStateUniversity-3-1024x575.jpeg 1024w, https:\/\/tracingrace.iastatedigital.org\/asian-womeninstem-isu\/wp-content\/uploads\/2023\/07\/cropped-IowaStateUniversity-3-768x432.jpeg 768w, https:\/\/tracingrace.iastatedigital.org\/asian-womeninstem-isu\/wp-content\/uploads\/2023\/07\/cropped-IowaStateUniversity-3-1536x863.jpeg 1536w\" sizes=\"auto, (max-width: 1920px) 100vw, 1920px\" \/><div class=\"wp-block-cover__inner-container is-layout-flow wp-block-cover-is-layout-flow\">\n<h3 class=\"wp-block-heading has-text-align-center has-large-font-size\">Professor Anwesha Sarkar<\/h3>\n<\/div><\/div>\n\n\n\n<div style=\"height:37px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-media-text alignwide is-stacked-on-mobile\" style=\"grid-template-columns:27% auto\"><figure class=\"wp-block-media-text__media\"><img loading=\"lazy\" decoding=\"async\" width=\"605\" height=\"605\" src=\"https:\/\/tracingrace.iastatedigital.org\/asian-womeninstem-isu\/wp-content\/uploads\/2023\/07\/Anwesha-Sarkar-1.jpeg\" alt=\"\" class=\"wp-image-252 size-full\" srcset=\"https:\/\/tracingrace.iastatedigital.org\/asian-womeninstem-isu\/wp-content\/uploads\/2023\/07\/Anwesha-Sarkar-1.jpeg 605w, https:\/\/tracingrace.iastatedigital.org\/asian-womeninstem-isu\/wp-content\/uploads\/2023\/07\/Anwesha-Sarkar-1-300x300.jpeg 300w, https:\/\/tracingrace.iastatedigital.org\/asian-womeninstem-isu\/wp-content\/uploads\/2023\/07\/Anwesha-Sarkar-1-150x150.jpeg 150w\" sizes=\"auto, (max-width: 605px) 100vw, 605px\" \/><\/figure><div class=\"wp-block-media-text__content\">\n<p class=\"wp-block-paragraph\">Introducing Dr. Anwesha Sarkar, an accomplished Assistant Professor at Iowa State University. With a diverse academic background spanning multiple continents, her expertise lies in the fascinating realm of Single Molecule Biophysics, Atomic Force Microscopy, and Protein-protein interactions. As a vital contributor to the Nanovaccine Institute, Dr. Sarkar&#8217;s research delves into the cutting-edge world of biosensors and bioengineering, propelling advancements in the field of nanovaccines. Her journey is a testament to the power of interdisciplinary collaboration and the pursuit of scientific excellence.<\/p>\n\n\n\n<h6 class=\"wp-block-heading\"><strong>Education<\/strong>&nbsp;<\/h6>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Postdoctoral Research Associate, Iowa State University (2020) PhD<\/li>\n\n\n\n<li>Physics, Wayne State University (2015) MPhil, Physics<\/li>\n\n\n\n<li>Institute of Physics, India (2011) MSc, <\/li>\n\n\n\n<li>Physics, IIT Madras, India (2010) BSc, <\/li>\n\n\n\n<li>Physics, ST. Xavier\u2019s College, Kolkata, India (2008) &nbsp;<\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">                                      Email:&nbsp;<a href=\"mailto:anweshas@iastate.edu\">anweshas@iastate.edu<\/a><\/p>\n\n\n\n<div class=\"wp-block-media-text alignwide has-media-on-the-right is-stacked-on-mobile\"><div class=\"wp-block-media-text__content\">\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-8f761849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:100%\">\n<p class=\"has-medium-font-size wp-block-paragraph\"><strong> BACM LAB &#8211; Research Laboratory of Professor     Anwesha Sarkar<\/strong><\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/sites.google.com\/iastate.edu\/bacm-lab\/home?authuser=0\">Visit Website<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div><figure class=\"wp-block-media-text__media\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"535\" src=\"https:\/\/tracingrace.iastatedigital.org\/asian-womeninstem-isu\/wp-content\/uploads\/2023\/07\/Screenshot-2023-07-30-at-7.59.43-PM-1024x535.png\" alt=\"\" class=\"wp-image-253 size-full\" srcset=\"https:\/\/tracingrace.iastatedigital.org\/asian-womeninstem-isu\/wp-content\/uploads\/2023\/07\/Screenshot-2023-07-30-at-7.59.43-PM-1024x535.png 1024w, https:\/\/tracingrace.iastatedigital.org\/asian-womeninstem-isu\/wp-content\/uploads\/2023\/07\/Screenshot-2023-07-30-at-7.59.43-PM-300x157.png 300w, https:\/\/tracingrace.iastatedigital.org\/asian-womeninstem-isu\/wp-content\/uploads\/2023\/07\/Screenshot-2023-07-30-at-7.59.43-PM-768x401.png 768w, https:\/\/tracingrace.iastatedigital.org\/asian-womeninstem-isu\/wp-content\/uploads\/2023\/07\/Screenshot-2023-07-30-at-7.59.43-PM-1536x803.png 1536w, https:\/\/tracingrace.iastatedigital.org\/asian-womeninstem-isu\/wp-content\/uploads\/2023\/07\/Screenshot-2023-07-30-at-7.59.43-PM-2048x1070.png 2048w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure><\/div>\n\n\n\n<h6 class=\"wp-block-heading alignwide\">Publications<\/h6>\n\n\n\n<div class=\"wp-block-columns alignwide is-layout-flex wp-container-core-columns-is-layout-8f761849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<ul class=\"wp-block-list\">\n<li>Waite, J., Tana, S., Saha, H., Sarkar, S., Sarkar, A. (2022). Few-shot Deep Learning for AFM Force Curve Characterization of Single Molecule Interactions. Accepted in Patterns<\/li>\n\n\n\n<li>Rade, J., Zhang, J., Sarkar, S., Krishnamurthy, A., Ren, J., &amp; Sarkar, A. (2022). Deep Learning for Live Cell Shape Detection and Automated AFM Navigation. Bioengineering, 9(10), 522.<\/li>\n\n\n\n<li>Sarkar, A. (December 2021). Biosensing, characterization of biosensors, and improved drug delivery approaches using Atomic Force Microscopy: A review. Frontiers in Nanotechnology<\/li>\n\n\n\n<li>Sarkar, A*., Mao, S.*, Wang, Y., Song, C., LeVine, D., Wang, X., and Que, L. (2021). Microfluidic chip grafted with integrin tension sensors for evaluating the effects of flowing shear force and ROCK inhibitor on platelets. Lab on a chip, (* made equal contribution and they share the first authorship)<\/li>\n\n\n\n<li>Sarkar, A., LeVine, D. N., Kuzmina, N., Zhao, Y., &amp; Wang, X. (2020). Cell migration driven by self-generated integrin ligand gradient on ligand-labile surfaces. Current Biology, 30(20), 4022-4032. doi:<a href=\"https:\/\/www.google.com\/url?q=https%3A%2F%2Fdoi.org%2F10.1016%2Fj.cub.2020.08.020&amp;sa=D&amp;sntz=1&amp;usg=AOvVaw37LxWrARnFBycpfrkQX1C0\" target=\"_blank\" rel=\"noreferrer noopener\">&nbsp;<\/a><a href=\"https:\/\/www.google.com\/url?q=https%3A%2F%2Fdoi.org%2F10.1016%2Fj.cub.2020.08.020&amp;sa=D&amp;sntz=1&amp;usg=AOvVaw37LxWrARnFBycpfrkQX1C0\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.1016\/j.cub.2020.08.020<\/a><\/li>\n\n\n\n<li>Sarkar, A., LeVine, D., Zhao, Y., Mollaeian, K., Ren, J., &amp; Wang, X. (2020). Tandem tension sensor reveals substrate rigidity-dependence of integrin molecular tensions in live cells. bioRxiv. doi:<a href=\"https:\/\/www.google.com\/url?q=https%3A%2F%2Fdoi.org%2F10.1101%2F2020.01.24.918946&amp;sa=D&amp;sntz=1&amp;usg=AOvVaw2y_ZEQpXj35swUn3_834Ho\" target=\"_blank\" rel=\"noreferrer noopener\">&nbsp;<\/a><a href=\"https:\/\/www.google.com\/url?q=https%3A%2F%2Fdoi.org%2F10.1101%2F2020.01.24.918946&amp;sa=D&amp;sntz=1&amp;usg=AOvVaw2y_ZEQpXj35swUn3_834Ho\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.1101\/2020.01.24.918946<\/a><\/li>\n\n\n\n<li>Zhao, Y., Sarkar, A., &amp; Wang, X. (2020). Peptide nucleic acid based tension sensor for cellular force imaging with strong DNase resistance. Biosensors and Bioelectronics, 150, 111959. doi:<a href=\"https:\/\/www.google.com\/url?q=https%3A%2F%2Fdoi.org%2F10.1016%2Fj.bios.2019.111959&amp;sa=D&amp;sntz=1&amp;usg=AOvVaw0ytrrvHa7ANApKKA4bDtRg\" target=\"_blank\" rel=\"noreferrer noopener\">&nbsp;<\/a><a href=\"https:\/\/www.google.com\/url?q=https%3A%2F%2Fdoi.org%2F10.1016%2Fj.bios.2019.111959&amp;sa=D&amp;sntz=1&amp;usg=AOvVaw0ytrrvHa7ANApKKA4bDtRg\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.1016\/j.bios.2019.111959<\/a><\/li>\n\n\n\n<li>Wang, Y., Zhao, Y., Sarkar, A., &amp; Wang, X. (2019). Optical sensor revealed abnormal nuclease spatial activity on cancer cell membrane. Journal of biophotonics, 12(5), e201800351. DOI: 10.1002\/jbio.201800351<\/li>\n\n\n\n<li>Sarkar, A., Zhao, Y., Wang, Y., &amp; Wang, X. (2018). Force-activatable coating enables high-resolution cellular force imaging directly on regular cell culture surfaces. Physical biology, 15(6), 065002. doi: 10.1088\/1478-3975\/aac69d<\/li>\n\n\n\n<li>Wang, Y., LeVine, D. N., Gannon, M., Zhao, Y., Sarkar, A., Hoch, B., &amp; Wang, X. (2018). Force-activatable biosensor enables single platelet force mapping directly by fluorescence imaging. Biosensors and Bioelectronics, 100, 192-200. DOI: 10.1016\/j.bios.2017.09.007<\/li>\n\n\n\n<li>Zhao, Y., Wang, Y., Sarkar, A., &amp; Wang, X. (2018). Keratocytes generate high integrin tension at the trailing edge to mediate rear De-adhesion during rapid cell migration. Iscience, 9, 502-512. doi:<a href=\"https:\/\/www.google.com\/url?q=https%3A%2F%2Fdoi.org%2F10.1016%2Fj.isci.2018.11.016&amp;sa=D&amp;sntz=1&amp;usg=AOvVaw3sLoF7JS3gzUn7IStQ8I4Y\" target=\"_blank\" rel=\"noreferrer noopener\">&nbsp;<\/a><a href=\"https:\/\/www.google.com\/url?q=https%3A%2F%2Fdoi.org%2F10.1016%2Fj.isci.2018.11.016&amp;sa=D&amp;sntz=1&amp;usg=AOvVaw3sLoF7JS3gzUn7IStQ8I4Y\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.1016\/j.isci.2018.11.016<\/a><\/li>\n\n\n\n<li>Sarkar, A.#, Sohail, A., Dong, J., Prunotto, M., Shinki, K., Fridman, R., &amp; Hoffmann, P. M. (2019). Live cell measurements of interaction forces and binding kinetics between Discoidin Domain Receptor 1 (DDR1) and collagen I with atomic force microscopy. Biochimica et Biophysica Acta (BBA)-General Subjects, 1863(11), 129402. DOI: 10.1016\/j.bbagen.2019.07.011<\/li>\n\n\n\n<li>Jones, S. K., Sarkar, A.#, Feldmann, D. P., Hoffmann, P., &amp; Merkel, O. M. (2017). Revisiting the value of competition assays in folate receptor-mediated drug delivery. Biomaterials, 138, 35-45. doi: https:\/\/doi.org\/10.1016\/j.biomaterials.2017.05.034<\/li>\n<\/ul>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<ul class=\"wp-block-list\">\n<li>J. Rade, S. Sarkar, A. Krishnamurthy, A. Sarkar, Virtual AFM: Generating Synthetic 2D Multi-view Images from 3D Protein Structure, Biomedical Engineering Society (BMES) Annual meeting, San Antonio, TX, 2022.<\/li>\n\n\n\n<li>A. Koep, A. Sarkar, S. Alam, T. Prozorov, I. Schneider, Actuatable Hollow DNA Origami Drug Delivery Constructs, Biomedical Engineering Society (BMES) Annual meeting, San Antonio, TX, 2022.<\/li>\n\n\n\n<li>J. Rade, S. Sarkar, A. Sarkar, A. Krishnamurthy, 3D Reconstruction of Protein Complex Structures Using Synthesized Multi-View AFM Images, Machine Learning in Structural Biology (MLSB) Workshop at the 36th Conference on Neural Information Processing Systems (NeurIPS), New Orleans, LA, 2022.<\/li>\n\n\n\n<li>A. Sarkar, N. Hassan, R. Bardhan, Multimodal characterization of live cancer cells using Atomic Force Microscopy and Raman spectroscopy, presented as a poster, Biophysical Society 66th Annual Meeting, San Francisco, CA 2022.<\/li>\n\n\n\n<li>A. Sarkar, S. Yang, B. Chen, High Resolution Single Molecule Imaging of WRC-Rac1 Protein Complex with Atomic Force Microscopy, Biomedical Engineering Society (BMES) Annual meeting, Orlando, Fl 2021.<\/li>\n\n\n\n<li>J. Rade, S. Sarkar, A. Krishnamurthy, J. Ren, A. Sarkar, AI Guided Measurement of Live Cells Using AFM, Modelling, Estimation and Control Conference (MECC), Austin, TX 2021.<\/li>\n\n\n\n<li>A. Sarkar, J. Waite, S. Sarkar, Deep learning for fast Atomic Force Microscopy data analytics, selected for platform presentation and presented as a talk, Biophysical Society 65th Annual Meeting (virtual) 2021.<\/li>\n\n\n\n<li>S. Mao~ , A. Sarkar ~, D. LeVine, X. Wang, L. Que, Studies of the drug treatment effects on platelets using integrative tension sensors embedded in a microfuidic chip, Microfluidics for Hematology, presented as talk, Chicago, IL 2020 (~ made equal contribution and share the first authorship)<\/li>\n\n\n\n<li>A. Sarkar, Y. Wang, X. Wang, Determining Integrin Molecular Tension for the Recruitment and the activation of Focal Adhesion Kinase, Biophysical Society (BPS), 63rd Annual meeting, presented as poster, Baltimore, MD 2019.<\/li>\n\n\n\n<li>A. Sarkar, X. Wang, Integrin molecular tensions in live cells are altered by substrate rigidity, Biophysical Society (BPS), 62nd Annual meeting, presented as a talk and poster, San Francisco, CA 2018 [the work was also presented as a talk and poster in the ISU Research Day, Iowa State University, 2018]<\/li>\n\n\n\n<li>A. Sarkar, R. Fridman, A. Sohail and P. M. Hoffmann, Measurement of DDR-Collagen interaction Forces with Atomic force Microscopy, American Physical Society (APS) March Meeting, San Antonio, TX 2015<\/li>\n\n\n\n<li>A. Sarkar, E. Mayyas and P. M. Hofmann, Effect of Surface Density of Active sites on Rupture Force Distributions of Single Molecule Interactions, Biophysical Society (BPS), 59th Annual Meeting, Baltimore, MD 2015<\/li>\n\n\n\n<li>A. Sarkar and P. M. Hoffmann, Effect of active site density on rupture force distributions in ligand-protein force measurements, American Physical Society (APS) Ohio-Region Section Meeting, April 2014, Youngstown, OH (presented as poster) [the work was also presented during the Physics Graduate Research Day, Wayne State University, April 2014]<\/li>\n\n\n\n<li>A. Sarkar, E. Kramkowski, E. Mayyas and P. M. Hoffmann, Multiple attachments, heterogeneous binding and the high force tail in protein-protein binding force histograms, American Physical Society (APS) March Meeting, March 2013, Baltimore, MD (presented as poster) [the work was also presented during the Physics Graduate Research Day, Wayne State University, April 2013]<\/li>\n\n\n\n<li>A. Sarkar, E. Kramkowski and P. M. Hoffmann, Live cell imaging and determination of protein-protein rupture force with AFM, American Physical Society (APS) Ohio-Region Section Meeting, October 2012, Detroit, MI (presented as poster) [the work was also presented in Michigan Microscopy and Microanalysis Society Fall 2012 Meeting]<\/li>\n<\/ul>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Email:&nbsp;anweshas@iastate.edu Publications<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-251","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/tracingrace.iastatedigital.org\/asian-womeninstem-isu\/wp-json\/wp\/v2\/posts\/251","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/tracingrace.iastatedigital.org\/asian-womeninstem-isu\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/tracingrace.iastatedigital.org\/asian-womeninstem-isu\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/tracingrace.iastatedigital.org\/asian-womeninstem-isu\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/tracingrace.iastatedigital.org\/asian-womeninstem-isu\/wp-json\/wp\/v2\/comments?post=251"}],"version-history":[{"count":3,"href":"https:\/\/tracingrace.iastatedigital.org\/asian-womeninstem-isu\/wp-json\/wp\/v2\/posts\/251\/revisions"}],"predecessor-version":[{"id":328,"href":"https:\/\/tracingrace.iastatedigital.org\/asian-womeninstem-isu\/wp-json\/wp\/v2\/posts\/251\/revisions\/328"}],"wp:attachment":[{"href":"https:\/\/tracingrace.iastatedigital.org\/asian-womeninstem-isu\/wp-json\/wp\/v2\/media?parent=251"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/tracingrace.iastatedigital.org\/asian-womeninstem-isu\/wp-json\/wp\/v2\/categories?post=251"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/tracingrace.iastatedigital.org\/asian-womeninstem-isu\/wp-json\/wp\/v2\/tags?post=251"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}